The recent advancements in semi-synthetic minimal cell (SSMC) technology paves the way to several interesting scenarios that span from basic scientific advancements to applications in biotechnology. In this short chapter we discuss the relevance of establishing chemical communication between synthetic and natural cells as an important conceptual question, and then discuss it as a new bio/chemical-information & communication technology. At this aim, the state-of-the-art of SSMCs technology is shortly reviewed, and a possible experimental ap-proach based on bacteria quorum sensing mechanisms is proposed and discussed.
Stano, P., Rampioni, G., Damiano, L., D’Angelo, F., Carrara, P., Leoni, L., et al. (2014). Towards the engineering of chemical communication between semi-synthetic and natural cells. In Evolution, complexity and artificial life (pp. 91-104). Berlin : Springer Berlin Heidelberg [10.1007/978-3-642-37577-4_6].