The present invention relates to the therapeutic utilizzation of the preparation of lactoferrin and desferrioxamine metalsulphonate for the therapy of many acute or recurrent viral infectious diseases in humans and animals. In details, the present invention demonstrates the antiviral activity, based on the inhibition either of the absorption either of the replication of several virus, possessed by a preparation of lactoferrin (or its anologous proteins like transferrins) in apo or iron or other metal ions saturated forms, together with desferrioxamine metansulfonate (or other metal ion chelators like 8-idroxiquinoline 1,10phenanthroline, phosphonoacetic acid). This antiviral activity is well evident towards DNA virus, like Herpersviruses, and towards RNA virus, like Rhinovirus, and can be generally extended and utilized for the therapy of many acute or recurrent viral infections concerning skin, mucosas or other tissues.
Valenti, P., Antonini, G. (1996)PREPARATION OF LACTOFERRIN (OR ANALOGOUS PROTEINS) AND DESFERRIOXAMINE METHANESULFONATE (OR OTHER METAL ION CHELATORS) FOR THE THERAPY OF VIRAL INFECTIOUS DISEASES. . Brevetto No. CA2180683 (A1).
PREPARATION OF LACTOFERRIN (OR ANALOGOUS PROTEINS) AND DESFERRIOXAMINE METHANESULFONATE (OR OTHER METAL ION CHELATORS) FOR THE THERAPY OF VIRAL INFECTIOUS DISEASES
ANTONINI, GIOVANNI
1996-01-01
Abstract
The present invention relates to the therapeutic utilizzation of the preparation of lactoferrin and desferrioxamine metalsulphonate for the therapy of many acute or recurrent viral infectious diseases in humans and animals. In details, the present invention demonstrates the antiviral activity, based on the inhibition either of the absorption either of the replication of several virus, possessed by a preparation of lactoferrin (or its anologous proteins like transferrins) in apo or iron or other metal ions saturated forms, together with desferrioxamine metansulfonate (or other metal ion chelators like 8-idroxiquinoline 1,10phenanthroline, phosphonoacetic acid). This antiviral activity is well evident towards DNA virus, like Herpersviruses, and towards RNA virus, like Rhinovirus, and can be generally extended and utilized for the therapy of many acute or recurrent viral infections concerning skin, mucosas or other tissues.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.