The study of the reactivity of oxazolidin-2-ones versus acylating agents (anhydrides or acyl chlorides) in solutions containing an electro- generated base has allowed us to establish a new methodology for the acylation of Evans’ chiral auxiliaries under mild conditions and to avoid any possible epimerization.
Sotgiu, G., M., F., A., I., L., P., L., R. (2001). Electrogenerated base induced N-acylation of chiral oxazolidin-2-ones. JOURNAL OF ORGANIC CHEMISTRY, 66(18), 6185-6188 [10.1021/jo010038+].
Electrogenerated base induced N-acylation of chiral oxazolidin-2-ones
SOTGIU, Giovanni;
2001-01-01
Abstract
The study of the reactivity of oxazolidin-2-ones versus acylating agents (anhydrides or acyl chlorides) in solutions containing an electro- generated base has allowed us to establish a new methodology for the acylation of Evans’ chiral auxiliaries under mild conditions and to avoid any possible epimerization.File in questo prodotto:
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