We present here a brief description of the relationships among metals, nitric oxide metabolism, and ageing. In particular, we will discuss the interactions occurring between redox (copper, iron) and non-redox (zinc) metals and nitric oxide, the metal- and nitric oxide-catalyzed formation of thiol adducts (nitrosothiols, mixed disulphides) and the possible involvement of these species in the ageing process.
Musci, G., Persichini, T., Casadei, M., Mazzone, V., Venturini, G., Polticelli, F., et al. (2006). Nitrosative/oxidative modifications and ageing. MECHANISMS OF AGEING AND DEVELOPMENT, 127, 544-551 [10.1016/j.mad.2006.01.012].
Nitrosative/oxidative modifications and ageing
PERSICHINI, TIZIANA;VENTURINI, Giorgio;POLTICELLI, Fabio;COLASANTI, Marco
2006-01-01
Abstract
We present here a brief description of the relationships among metals, nitric oxide metabolism, and ageing. In particular, we will discuss the interactions occurring between redox (copper, iron) and non-redox (zinc) metals and nitric oxide, the metal- and nitric oxide-catalyzed formation of thiol adducts (nitrosothiols, mixed disulphides) and the possible involvement of these species in the ageing process.File in questo prodotto:
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