Fluorine-substituted hydroxyapatites are considered promising materials for bone scaffolding. In this study a systematic investigation on F-half substituted hydroxyapatite (F-HAp, Ca(10)(PO(4))(6)OHF) obtained by precipitation is reported. Results on composition analysis, thermal behaviour, and sinterability are presented for a comparison with the respective pure hydroxyapatite. Samples were characterised by electron microscopy, induced coupled plasma-atomic emission spectroscopy, thermal analysis, infrared spectroscopy, N(2) adsorption measurements, X-ray diffraction and dilatometry. A semicrystalline F-substituted hydroxyapatite powder made up of needle-like nanoparticles was obtained. Notwithstanding that it was thermally stable up to 1300 degrees C, it was sintered at relatively low temperatures obtaining a very fine microstructure with a relevant nanoporosity, beneficial in view of cell adhesion and in-growth. Hardness, elastic modulus and toughness of produced samples were investigated by Vickers-Knoop microhardness testing. Significant improvements of the mechanical properties were observed for the F-substituted hydroxyapatite, in comparison with pure hydroxyapatite. (C) 2009 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
Bianco, A., Cacciotti, I., Lombardi, M., Montanaro, L., Bemporad, E., Sebastiani, M. (2010). F-substituted hydroxyapatite nanopowders: Thermal stability, sintering behaviour and mechanical properties. CERAMICS INTERNATIONAL, 36(1), 313-322 [10.1016/j.ceramint.2009.09.007].
F-substituted hydroxyapatite nanopowders: Thermal stability, sintering behaviour and mechanical properties
BEMPORAD, Edoardo;SEBASTIANI, MARCO
2010-01-01
Abstract
Fluorine-substituted hydroxyapatites are considered promising materials for bone scaffolding. In this study a systematic investigation on F-half substituted hydroxyapatite (F-HAp, Ca(10)(PO(4))(6)OHF) obtained by precipitation is reported. Results on composition analysis, thermal behaviour, and sinterability are presented for a comparison with the respective pure hydroxyapatite. Samples were characterised by electron microscopy, induced coupled plasma-atomic emission spectroscopy, thermal analysis, infrared spectroscopy, N(2) adsorption measurements, X-ray diffraction and dilatometry. A semicrystalline F-substituted hydroxyapatite powder made up of needle-like nanoparticles was obtained. Notwithstanding that it was thermally stable up to 1300 degrees C, it was sintered at relatively low temperatures obtaining a very fine microstructure with a relevant nanoporosity, beneficial in view of cell adhesion and in-growth. Hardness, elastic modulus and toughness of produced samples were investigated by Vickers-Knoop microhardness testing. Significant improvements of the mechanical properties were observed for the F-substituted hydroxyapatite, in comparison with pure hydroxyapatite. (C) 2009 Elsevier Ltd and Techna Group S.r.l. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
