Electrochemically induced synthesis of beta-lactams, by cyclization (via C3-C4 bond formation) of haloamides (XCHRCONRCHRR4)-C-1-C-2-R-3 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R-1-R-4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions
FEROCI M, ORSINI M, SOTGIU G, ROSSI L, & INESI A (2006). An electrochemical alternative strategy to the synthesis of β-lactams. Part 2. C3-C4 bond formation. ELECTROCHIMICA ACTA, 51(25), 5540-5547 [10.1016/j.electacta.2006.02.026].
Titolo: | An electrochemical alternative strategy to the synthesis of β-lactams. Part 2. C3-C4 bond formation | |
Autori: | ||
Data di pubblicazione: | 2006 | |
Rivista: | ||
Citazione: | FEROCI M, ORSINI M, SOTGIU G, ROSSI L, & INESI A (2006). An electrochemical alternative strategy to the synthesis of β-lactams. Part 2. C3-C4 bond formation. ELECTROCHIMICA ACTA, 51(25), 5540-5547 [10.1016/j.electacta.2006.02.026]. | |
Abstract: | Electrochemically induced synthesis of beta-lactams, by cyclization (via C3-C4 bond formation) of haloamides (XCHRCONRCHRR4)-C-1-C-2-R-3 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R-1-R-4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions | |
Handle: | http://hdl.handle.net/11590/143448 | |
Appare nelle tipologie: | 1.1 Articolo in rivista |