Electrochemical carboxylation of N-(2-bromopropionyl)-4R-phenyloxazolidin-2-one aimed at the synthesis and chiral resolution of unsymmetrical methylmalonic ester derivatives is described. The presence of the Evans’ chiral auxiliary permits an easy resolution of the mixture of the two diastereoisomers.

Feroci, M., Inesi, A., Orsini, M., Palombi, L. (2002). Electrochemical Carboxylation of N-(2-Bromopropionyl)-4R-phenyloxazolidin-2-one: An Efficient Route to Unsymmetrical Methylmalonic Ester Derivatives. ORGANIC LETTERS, 16, 2617-2620.

Electrochemical Carboxylation of N-(2-Bromopropionyl)-4R-phenyloxazolidin-2-one: An Efficient Route to Unsymmetrical Methylmalonic Ester Derivatives

ORSINI, MONICA;
2002-01-01

Abstract

Electrochemical carboxylation of N-(2-bromopropionyl)-4R-phenyloxazolidin-2-one aimed at the synthesis and chiral resolution of unsymmetrical methylmalonic ester derivatives is described. The presence of the Evans’ chiral auxiliary permits an easy resolution of the mixture of the two diastereoisomers.
2002
Feroci, M., Inesi, A., Orsini, M., Palombi, L. (2002). Electrochemical Carboxylation of N-(2-Bromopropionyl)-4R-phenyloxazolidin-2-one: An Efficient Route to Unsymmetrical Methylmalonic Ester Derivatives. ORGANIC LETTERS, 16, 2617-2620.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/146244
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