Electrochemically induced synthesis of beta-lactams, by cyclization (via C3-C4 bond formation) of haloamides (XCHRCONRCHRR4)-C-1-C-2-R-3 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R-1-R-4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions.

Feroci, M., Orsini, M., Sotgiu, G., Rossi, L., Inesi, A. (2006). An electrochemical alternative strategy to the synthesis of β-lactams. Part 2 [1] C3-C4 Bond formation. ELECTROCHIMICA ACTA, 51, 5540-5547.

An electrochemical alternative strategy to the synthesis of β-lactams. Part 2 [1] C3-C4 Bond formation

ORSINI, MONICA;SOTGIU, Giovanni;
2006-01-01

Abstract

Electrochemically induced synthesis of beta-lactams, by cyclization (via C3-C4 bond formation) of haloamides (XCHRCONRCHRR4)-C-1-C-2-R-3 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R-1-R-4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions.
Feroci, M., Orsini, M., Sotgiu, G., Rossi, L., Inesi, A. (2006). An electrochemical alternative strategy to the synthesis of β-lactams. Part 2 [1] C3-C4 Bond formation. ELECTROCHIMICA ACTA, 51, 5540-5547.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/149411
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