Biological interfaces characterized by a complex mixture of hydrophobic, hydrophilic, or charged moieties interfere with the cooperative rearrangement of the hydrogen-bond network of water. In the present study, this solute-induced dynamical perturbation is investigated by extended frequency range depolarized light scattering experiments on an aqueous solution of a variety of systems of different nature and complexity such as small hydrophobic and hydrophilic molecules, amino acids, dipeptides, and proteins. Our results suggest that a reductionist approach is not adequate to describe the rearrangement of hydration water because a significant increase of the dynamical retardation and extension of the perturbation occurs when increasing the chemical complexity of the solute.

Comez, L., Lupi, L., Morresi, A., Paolantoni, M., Sassi, P., & Fioretto, D. (2013). More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 4(7), 1188-92-1192 [10.1021/jz400360v].

More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water

Lupi, Laura;
2013

Abstract

Biological interfaces characterized by a complex mixture of hydrophobic, hydrophilic, or charged moieties interfere with the cooperative rearrangement of the hydrogen-bond network of water. In the present study, this solute-induced dynamical perturbation is investigated by extended frequency range depolarized light scattering experiments on an aqueous solution of a variety of systems of different nature and complexity such as small hydrophobic and hydrophilic molecules, amino acids, dipeptides, and proteins. Our results suggest that a reductionist approach is not adequate to describe the rearrangement of hydration water because a significant increase of the dynamical retardation and extension of the perturbation occurs when increasing the chemical complexity of the solute.
Comez, L., Lupi, L., Morresi, A., Paolantoni, M., Sassi, P., & Fioretto, D. (2013). More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 4(7), 1188-92-1192 [10.1021/jz400360v].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11590/351155
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 65
  • ???jsp.display-item.citation.isi??? 64
social impact