Biological interfaces characterized by a complex mixture of hydrophobic, hydrophilic, or charged moieties interfere with the cooperative rearrangement of the hydrogen-bond network of water. In the present study, this solute-induced dynamical perturbation is investigated by extended frequency range depolarized light scattering experiments on an aqueous solution of a variety of systems of different nature and complexity such as small hydrophobic and hydrophilic molecules, amino acids, dipeptides, and proteins. Our results suggest that a reductionist approach is not adequate to describe the rearrangement of hydration water because a significant increase of the dynamical retardation and extension of the perturbation occurs when increasing the chemical complexity of the solute.

Comez, L., Lupi, L., Morresi, A., Paolantoni, M., Sassi, P., Fioretto, D. (2013). More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 4(7), 1188-92-1192 [10.1021/jz400360v].

More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water

Lupi, Laura;
2013-01-01

Abstract

Biological interfaces characterized by a complex mixture of hydrophobic, hydrophilic, or charged moieties interfere with the cooperative rearrangement of the hydrogen-bond network of water. In the present study, this solute-induced dynamical perturbation is investigated by extended frequency range depolarized light scattering experiments on an aqueous solution of a variety of systems of different nature and complexity such as small hydrophobic and hydrophilic molecules, amino acids, dipeptides, and proteins. Our results suggest that a reductionist approach is not adequate to describe the rearrangement of hydration water because a significant increase of the dynamical retardation and extension of the perturbation occurs when increasing the chemical complexity of the solute.
2013
Comez, L., Lupi, L., Morresi, A., Paolantoni, M., Sassi, P., Fioretto, D. (2013). More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 4(7), 1188-92-1192 [10.1021/jz400360v].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/351155
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