SARS-CoV-2 is currently causing hundreds of deaths every day in European countries, mostly in not yet vaccinated elderly. Vaccine shortage poses relevant challenges to health authorities, called to act promptly with a scarcity of data. We modeled the mortality reduction of the elderly according to a schedule of mRNA SARS-CoV-2 vaccine that prioritized first dose administration. For the case study of Italy, we show an increase in protected individuals up to 53.4% and a decrease in deaths up to 19.8% in the cohort of over 80's compared with the standard vaccine recalls after 3 or 4 weeks. This model supports the adoption of vaccination campaigns that prioritize the administration of the first doses in the elderly.

Pontrelli, G., Cimini, G., Roversi, M., Gabrielli, A., Salina, G., Bernardi, S., et al. (2021). Prioritizing the First Doses of SARS-CoV-2 Vaccine to Save the Elderly: The Case Study of Italy. FRONTIERS IN PUBLIC HEALTH, 9, 684760 [10.3389/fpubh.2021.684760].

Prioritizing the First Doses of SARS-CoV-2 Vaccine to Save the Elderly: The Case Study of Italy

Gabrielli A.
Membro del Collaboration Group
;
2021-01-01

Abstract

SARS-CoV-2 is currently causing hundreds of deaths every day in European countries, mostly in not yet vaccinated elderly. Vaccine shortage poses relevant challenges to health authorities, called to act promptly with a scarcity of data. We modeled the mortality reduction of the elderly according to a schedule of mRNA SARS-CoV-2 vaccine that prioritized first dose administration. For the case study of Italy, we show an increase in protected individuals up to 53.4% and a decrease in deaths up to 19.8% in the cohort of over 80's compared with the standard vaccine recalls after 3 or 4 weeks. This model supports the adoption of vaccination campaigns that prioritize the administration of the first doses in the elderly.
Pontrelli, G., Cimini, G., Roversi, M., Gabrielli, A., Salina, G., Bernardi, S., et al. (2021). Prioritizing the First Doses of SARS-CoV-2 Vaccine to Save the Elderly: The Case Study of Italy. FRONTIERS IN PUBLIC HEALTH, 9, 684760 [10.3389/fpubh.2021.684760].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/395341
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