Human monocytes can differentiate into dendritic cells (DC) according to the nature of environmental signals. Pathogenic mycobacteria have been demonstrated interfere with this process to generate a not fully competent DC population. This mechanism is not common to non-pathogenic mycobacteria and could be correlated with bacterial virulence. However, it could represents a new mechanism of immune escape by persistent pathogens or a control mechanism of immune system to preserve the life of the organ against persistent infections. © 2005 Elsevier B.V. All rights reserved.

Martino, A., Sacchi, A., Colizzi, V., & Vendetti, S. (2006). Mycobacteria and dendritic cell differentiation: Escape or control of immunity. IMMUNOLOGY LETTERS, 102(1), 115-117 [10.1016/j.imlet.2005.06.016].

Mycobacteria and dendritic cell differentiation: Escape or control of immunity

Sacchi A.;
2006

Abstract

Human monocytes can differentiate into dendritic cells (DC) according to the nature of environmental signals. Pathogenic mycobacteria have been demonstrated interfere with this process to generate a not fully competent DC population. This mechanism is not common to non-pathogenic mycobacteria and could be correlated with bacterial virulence. However, it could represents a new mechanism of immune escape by persistent pathogens or a control mechanism of immune system to preserve the life of the organ against persistent infections. © 2005 Elsevier B.V. All rights reserved.
Martino, A., Sacchi, A., Colizzi, V., & Vendetti, S. (2006). Mycobacteria and dendritic cell differentiation: Escape or control of immunity. IMMUNOLOGY LETTERS, 102(1), 115-117 [10.1016/j.imlet.2005.06.016].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11590/400082
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