Although centrosome abnormalities are frequent in cancer, the mechanisms responsible for their accumulation are poorly understood. Here we comment on our recent publication identifying a new type of selective autophagy, named doryphagy, which preserves centrosome organization through targeting Centriolar Satellites (CS). Thus, doryphagy prevents inaccurate mitosis and genomic instability.

Cianfanelli, V., Cecconi, F. (2020). Doryphagy: when selective autophagy safeguards centrosome integrity. MOLECULAR & CELLULAR ONCOLOGY, 7(2), 1719021 [10.1080/23723556.2020.1719021].

Doryphagy: when selective autophagy safeguards centrosome integrity

Cianfanelli, Valentina
;
Cecconi, Francesco
2020-01-01

Abstract

Although centrosome abnormalities are frequent in cancer, the mechanisms responsible for their accumulation are poorly understood. Here we comment on our recent publication identifying a new type of selective autophagy, named doryphagy, which preserves centrosome organization through targeting Centriolar Satellites (CS). Thus, doryphagy prevents inaccurate mitosis and genomic instability.
2020
Cianfanelli, V., Cecconi, F. (2020). Doryphagy: when selective autophagy safeguards centrosome integrity. MOLECULAR & CELLULAR ONCOLOGY, 7(2), 1719021 [10.1080/23723556.2020.1719021].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/423228
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