LEONE, STEFANO
LEONE, STEFANO
A functional drug re-purposing screening identifies carfilzomib as a drug preventing 17β-estradiol: ERα signaling and cell proliferation in breast cancer cells.
2018-01-01 Busonero, Claudia; Leone, Stefano; Klemm, C; Acconcia, F.
A functional genetic screen for metabolic proteins unveils GART and the de novo purine biosynthetic pathway as novel targets for the treatment of luminal A ERa expressing primary and metastatic invasive ductal carcinoma
2023-01-01 Cipolletti, Manuela; Leone, Stefano; Bartoloni, Stefania; Acconcia, Filippo
A high throughput method to study the physiology of E2:ERα signaling in breast cancer cells.
2018-01-01 Leone, Stefano; Busonero, Claudia; Acconcia, Filippo
A New Anti-Estrogen Discovery Platform Identifies FDA-Approved Imidazole Anti-Fungal Drugs as Bioactive Compounds Against ERalpha Expressing Breast Cancer Cells
2021-01-01 Cipolletti, M; Bartoloni, S; Busonero, C; Parente, M; Leone, S; Acconcia, F
alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells.
2004-01-01 Cavalieri, E.; Mariotto, S.; Fabrizi, C.; DE PRATI, A. C.; Gottardo, R.; Leone, Stefano; Berra, L. V.; Lauro, Giuliana Maria; Ciampa, A. R.; Suzuki, H.
Clinically relevant CHK1 inhibitors abrogate wild-type and Y537S mutant ERα expression and proliferation in luminal primary and metastatic breast cancer cells
2022-01-01 Pescatori, Sara; Leone, Stefano; Cipolletti, Manuela; Bartoloni, Stefania; DI MASI, Alessandra; Acconcia, Filippo
Combretastatin A-4 induces p53 mitochondrial-relocalisation independent-apoptosis in non-small lung cancer cells.
2014-01-01 MENDEZ CALLEJAS, GINA MARCELA; Leone, Stefano; Tanzarella, Caterina; Antoccia, Antonio
Coordinate induction of humoral and spike specific t‐cell response in a cohort of italian health care workers receiving bnt162b2 mrna vaccine
2021-01-01 Agrati, C.; Castilletti, C.; Goletti, D.; Meschi, S.; Sacchi, A.; Matusali, G.; Bordoni, V.; Petrone, L.; Lapa, D.; Notari, S.; Vanini, V.; Colavita, F.; Aiello, A.; Agresta, A.; Farroni, C.; Grassi, G.; Leone, S.; Vaia, F.; Capobianchi, M. R.; Ippolito, G.; Puro, V.
Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation
2016-01-01 Totta, Pierangela; Busonero, Claudia; Leone, Stefano; Marino, Maria; Acconcia, Filippo
Emetine induces estrogen receptor alpha degradation and prevents 17β-estradiol-induced breast cancer cell proliferation
2017-01-01 Busonero, Claudia; Leone, Stefano; Acconcia, Filippo
ERβ-dependent neuroglobin up-regulation impairs 17β-estradiol-induced apoptosis in DLD-1 colon cancer cells upon oxidative stress injury
2015-01-01 Fiocchetti, Marco; Camilli, Giulia; Acconcia, Filippo; Leone, Stefano; Ascenzi, Paolo; Marino, Maria
Extracellular neuroglobin as a stress-induced factor activating pre-adaptation mechanisms against oxidative stress and chemotherapy-induced cell death in breast cancer
2020-01-01 Fiocchetti, M.; Fernandez, V. S.; Segatto, M.; Leone, S.; Cercola, P.; Massari, A.; Cavaliere, F.; Marino, M.
Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles
2022-01-01 Incerpi, Sandra; Gionfra, Fabio; De Luca, Roberto; Candelotti, Elena; De Vito, Paolo; Percario, Zulema A.; Leone, Stefano; Gnocchi, Davide; Rossi, Miriam; Caruso, Francesco; Scapin, Sergio; Davis, Paul J.; Lin, Hung-Yun; Affabris, Elisabetta; Pedersen, Jens Z.
G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells
2019-01-01 Berardinelli, F.; Tanori, M.; Muoio, D.; Buccarelli, M.; Di Masi, A.; Leone, S.; Ricci-Vitiani, L.; Pallini, R.; Mancuso, M.; Antoccia, A.
G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells
2020-01-01 Amato, Roberta; Valenzuela, Martina; Berardinelli, Francesco; Salvati, Erica; Maresca, Carmen; Leone, Stefano; Antoccia, Antonio; Sgura, Antonella
HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity
2015-01-01 Mangino, Giorgio; Famiglietti, Marylinda; Capone, Caterina; Veroni, Caterina; Percario, ZULEMA ANTONIA; Leone, Stefano; Fiorucci, Gianna; Lülf, Sebastian; Romeo, Giovanna; Agresti, Cristina; Persichini, Tiziana; Geyer, Matthias; Affabris, Elisabetta
HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2
2011-01-01 Mangino, G; Percario, ZULEMA ANTONIA; Fiorucci, G; Vaccari, G; Acconcia, Filippo; Chiarabelli, Cristiano; Leone, Stefano; Noto, Alessia; Horenkamp, Fa; Manrique, S; Romeo, G; Polticelli, Fabio; Geyer, M; Affabris, Elisabetta
HIV‐1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line
2022-01-01 Aiello, A.; Giannessi, F.; Percario, Z. A.; Fecchi, K.; Arenaccio, C.; Leone, S.; Carollo, M.; D'Aversa, E.; Chaperot, L.; Gambari, R.; Sargiacomo, M.; Affabris, E.
Hsp90 alpha regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks
2017-01-01 Pennisi, Rosa; Antoccia, Antonio; Leone, Stefano; Ascenzi, Paolo; DI MASI, Alessandra
In silico screening for ERα down modulators identifies thioridazine as an anti-proliferative agent in primary, 4OH-tamoxifen-resistant and Y537S ERα-expressing breast cancer cells.
2018-01-01 Busonero, C; Leone, S; Bianchi, F; Acconcia, F
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A functional drug re-purposing screening identifies carfilzomib as a drug preventing 17β-estradiol: ERα signaling and cell proliferation in breast cancer cells. | 1-gen-2018 | Busonero, Claudia; Leone, Stefano; Klemm, C; Acconcia, F. | |
| A functional genetic screen for metabolic proteins unveils GART and the de novo purine biosynthetic pathway as novel targets for the treatment of luminal A ERa expressing primary and metastatic invasive ductal carcinoma | 1-gen-2023 | Cipolletti, Manuela; Leone, Stefano; Bartoloni, Stefania; Acconcia, Filippo | |
| A high throughput method to study the physiology of E2:ERα signaling in breast cancer cells. | 1-gen-2018 | Leone, Stefano; Busonero, Claudia; Acconcia, Filippo | |
| A New Anti-Estrogen Discovery Platform Identifies FDA-Approved Imidazole Anti-Fungal Drugs as Bioactive Compounds Against ERalpha Expressing Breast Cancer Cells | 1-gen-2021 | Cipolletti, M; Bartoloni, S; Busonero, C; Parente, M; Leone, S; Acconcia, F | |
| alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells. | 1-gen-2004 | Cavalieri, E.; Mariotto, S.; Fabrizi, C.; DE PRATI, A. C.; Gottardo, R.; Leone, Stefano; Berra, L. V.; Lauro, Giuliana Maria; Ciampa, A. R.; Suzuki, H. | |
| Clinically relevant CHK1 inhibitors abrogate wild-type and Y537S mutant ERα expression and proliferation in luminal primary and metastatic breast cancer cells | 1-gen-2022 | Pescatori, Sara; Leone, Stefano; Cipolletti, Manuela; Bartoloni, Stefania; DI MASI, Alessandra; Acconcia, Filippo | |
| Combretastatin A-4 induces p53 mitochondrial-relocalisation independent-apoptosis in non-small lung cancer cells. | 1-gen-2014 | MENDEZ CALLEJAS, GINA MARCELA; Leone, Stefano; Tanzarella, Caterina; Antoccia, Antonio | |
| Coordinate induction of humoral and spike specific t‐cell response in a cohort of italian health care workers receiving bnt162b2 mrna vaccine | 1-gen-2021 | Agrati, C.; Castilletti, C.; Goletti, D.; Meschi, S.; Sacchi, A.; Matusali, G.; Bordoni, V.; Petrone, L.; Lapa, D.; Notari, S.; Vanini, V.; Colavita, F.; Aiello, A.; Agresta, A.; Farroni, C.; Grassi, G.; Leone, S.; Vaia, F.; Capobianchi, M. R.; Ippolito, G.; Puro, V. | |
| Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation | 1-gen-2016 | Totta, Pierangela; Busonero, Claudia; Leone, Stefano; Marino, Maria; Acconcia, Filippo | |
| Emetine induces estrogen receptor alpha degradation and prevents 17β-estradiol-induced breast cancer cell proliferation | 1-gen-2017 | Busonero, Claudia; Leone, Stefano; Acconcia, Filippo | |
| ERβ-dependent neuroglobin up-regulation impairs 17β-estradiol-induced apoptosis in DLD-1 colon cancer cells upon oxidative stress injury | 1-gen-2015 | Fiocchetti, Marco; Camilli, Giulia; Acconcia, Filippo; Leone, Stefano; Ascenzi, Paolo; Marino, Maria | |
| Extracellular neuroglobin as a stress-induced factor activating pre-adaptation mechanisms against oxidative stress and chemotherapy-induced cell death in breast cancer | 1-gen-2020 | Fiocchetti, M.; Fernandez, V. S.; Segatto, M.; Leone, S.; Cercola, P.; Massari, A.; Cavaliere, F.; Marino, M. | |
| Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles | 1-gen-2022 | Incerpi, Sandra; Gionfra, Fabio; De Luca, Roberto; Candelotti, Elena; De Vito, Paolo; Percario, Zulema A.; Leone, Stefano; Gnocchi, Davide; Rossi, Miriam; Caruso, Francesco; Scapin, Sergio; Davis, Paul J.; Lin, Hung-Yun; Affabris, Elisabetta; Pedersen, Jens Z. | |
| G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells | 1-gen-2019 | Berardinelli, F.; Tanori, M.; Muoio, D.; Buccarelli, M.; Di Masi, A.; Leone, S.; Ricci-Vitiani, L.; Pallini, R.; Mancuso, M.; Antoccia, A. | |
| G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells | 1-gen-2020 | Amato, Roberta; Valenzuela, Martina; Berardinelli, Francesco; Salvati, Erica; Maresca, Carmen; Leone, Stefano; Antoccia, Antonio; Sgura, Antonella | |
| HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity | 1-gen-2015 | Mangino, Giorgio; Famiglietti, Marylinda; Capone, Caterina; Veroni, Caterina; Percario, ZULEMA ANTONIA; Leone, Stefano; Fiorucci, Gianna; Lülf, Sebastian; Romeo, Giovanna; Agresti, Cristina; Persichini, Tiziana; Geyer, Matthias; Affabris, Elisabetta | |
| HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2 | 1-gen-2011 | Mangino, G; Percario, ZULEMA ANTONIA; Fiorucci, G; Vaccari, G; Acconcia, Filippo; Chiarabelli, Cristiano; Leone, Stefano; Noto, Alessia; Horenkamp, Fa; Manrique, S; Romeo, G; Polticelli, Fabio; Geyer, M; Affabris, Elisabetta | |
| HIV‐1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line | 1-gen-2022 | Aiello, A.; Giannessi, F.; Percario, Z. A.; Fecchi, K.; Arenaccio, C.; Leone, S.; Carollo, M.; D'Aversa, E.; Chaperot, L.; Gambari, R.; Sargiacomo, M.; Affabris, E. | |
| Hsp90 alpha regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks | 1-gen-2017 | Pennisi, Rosa; Antoccia, Antonio; Leone, Stefano; Ascenzi, Paolo; DI MASI, Alessandra | |
| In silico screening for ERα down modulators identifies thioridazine as an anti-proliferative agent in primary, 4OH-tamoxifen-resistant and Y537S ERα-expressing breast cancer cells. | 1-gen-2018 | Busonero, C; Leone, S; Bianchi, F; Acconcia, F |