ROTILI, DANTE
ROTILI, DANTE
Dipartimento di Scienze
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
2024-01-01 Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies
2012-01-01 Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile
2008-01-01 Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; ARMAND UGÓN, M; CLOTET CODINA, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents
2012-01-01 Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B.
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase
2005-01-01 Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation
2006-01-01 Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
2024-01-01 Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability
2017-01-01 Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, .
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib
2015-01-01 Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast
2005-01-01 Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts
2015-01-01 De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases
2011-01-01 Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. k., Leung; Mukram m, Mackeen; Ya Min, Tian; Peter j, Ratcliffe; Mai, Antonello; Benedikt m, Kessler; Christopher j, Schofield
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression
2022-01-01 Mouveaux, Thomas; Rotili, Dante; Boissavy, Tom; Roger, Emmanuel; Pierrot, Christine; Mai, Antonello; Gissot, Mathieu
Activation and inhibition of sirtuins: From bench to bedside
2024-01-01 Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases
2012-01-01 Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase
2006-01-01 Cirilli, R; Ferretti, R; Gallinella, B; LA TORRE, F; Mai, Antonello; Rotili, Dante
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
2021-01-01 Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Caccuri, Anna Maria; D'Acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
2023-01-01 Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T.; Mai, Antonello
At long last potent and selective KDM5 inhibitors
2016-01-01 Rotili, Dante; Mattevi, Andrea
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells
2012-01-01 Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling | 1-gen-2024 | Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman | |
| 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies | 1-gen-2012 | Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello | |
| 5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile | 1-gen-2008 | Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; ARMAND UGÓN, M; CLOTET CODINA, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello | |
| 6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents | 1-gen-2012 | Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B. | |
| 6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase | 1-gen-2005 | Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella | |
| 6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation | 1-gen-2006 | Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello | |
| A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection | 1-gen-2024 | Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic | |
| A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability | 1-gen-2017 | Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, . | |
| A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib | 1-gen-2015 | Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria | |
| A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast | 1-gen-2005 | Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici | |
| A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts | 1-gen-2015 | De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria | |
| A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases | 1-gen-2011 | Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. k., Leung; Mukram m, Mackeen; Ya Min, Tian; Peter j, Ratcliffe; Mai, Antonello; Benedikt m, Kessler; Christopher j, Schofield | |
| A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression | 1-gen-2022 | Mouveaux, Thomas; Rotili, Dante; Boissavy, Tom; Roger, Emmanuel; Pierrot, Christine; Mai, Antonello; Gissot, Mathieu | |
| Activation and inhibition of sirtuins: From bench to bedside | 1-gen-2024 | Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante | |
| An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases | 1-gen-2012 | Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng | |
| Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase | 1-gen-2006 | Cirilli, R; Ferretti, R; Gallinella, B; LA TORRE, F; Mai, Antonello; Rotili, Dante | |
| Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives | 1-gen-2021 | Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Caccuri, Anna Maria; D'Acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello | |
| Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII | 1-gen-2023 | Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T.; Mai, Antonello | |
| At long last potent and selective KDM5 inhibitors | 1-gen-2016 | Rotili, Dante; Mattevi, Andrea | |
| Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells | 1-gen-2012 | Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello |