We consider the estimation of mutation rates, using family data obtained from disputed paternity cases. It is shown how to take appropriate account of a number of complicating features—in particular, hidden mutation, differential mutation, and uncertain paternity—which can necessitate large corrections to simple estimates.

VICARD P, & DAWID A. P. (2004). A statistical treatment of biases affecting the estimation of mutation rates. MUTATION RESEARCH, 547, 19-33 [10.1016/j.mrfmmm.2003.11.005].

A statistical treatment of biases affecting the estimation of mutation rates

VICARD, Paola;
2004

Abstract

We consider the estimation of mutation rates, using family data obtained from disputed paternity cases. It is shown how to take appropriate account of a number of complicating features—in particular, hidden mutation, differential mutation, and uncertain paternity—which can necessitate large corrections to simple estimates.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11590/146392
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