Benvenuti nell'Anagrafe della Ricerca d'Ateneo

ROTILI, DANTE
 Distribuzione geografica
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Continente #
AS - Asia 4.242
EU - Europa 3.816
NA - Nord America 3.323
SA - Sud America 1.242
AF - Africa 117
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 12.747
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Nazione #
US - Stati Uniti d'America 3.204
NL - Olanda 1.914
SG - Singapore 1.699
RU - Federazione Russa 1.477
CN - Cina 1.171
BR - Brasile 910
VN - Vietnam 590
HK - Hong Kong 142
KR - Corea 134
IT - Italia 125
AR - Argentina 111
IN - India 97
DE - Germania 91
BD - Bangladesh 66
EC - Ecuador 65
CO - Colombia 55
CA - Canada 47
ID - Indonesia 47
MX - Messico 46
IQ - Iraq 40
ZA - Sudafrica 36
GB - Regno Unito 33
FR - Francia 32
TR - Turchia 29
JP - Giappone 28
PK - Pakistan 28
PH - Filippine 26
PY - Paraguay 26
AT - Austria 25
CL - Cile 23
VE - Venezuela 23
SA - Arabia Saudita 21
PL - Polonia 20
ES - Italia 19
UA - Ucraina 18
PE - Perù 16
UZ - Uzbekistan 16
MA - Marocco 15
SE - Svezia 13
EG - Egitto 12
MY - Malesia 12
AZ - Azerbaigian 11
TH - Thailandia 11
TN - Tunisia 11
KZ - Kazakistan 10
FI - Finlandia 8
UY - Uruguay 8
DZ - Algeria 7
JO - Giordania 7
LT - Lituania 7
AL - Albania 5
BO - Bolivia 5
ET - Etiopia 5
IE - Irlanda 5
IL - Israele 5
JM - Giamaica 5
KE - Kenya 5
NP - Nepal 5
OM - Oman 5
LB - Libano 4
NG - Nigeria 4
PT - Portogallo 4
SY - Repubblica araba siriana 4
TW - Taiwan 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BH - Bahrain 3
CH - Svizzera 3
CI - Costa d'Avorio 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
HN - Honduras 3
KH - Cambogia 3
LV - Lettonia 3
PA - Panama 3
QA - Qatar 3
XK - ???statistics.table.value.countryCode.XK??? 3
BF - Burkina Faso 2
BG - Bulgaria 2
BY - Bielorussia 2
GT - Guatemala 2
IR - Iran 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LK - Sri Lanka 2
MG - Madagascar 2
MW - Malawi 2
PS - Palestinian Territory 2
RO - Romania 2
RS - Serbia 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BE - Belgio 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BT - Bhutan 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
Totale 12.722
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Città #
Amsterdam 1.866
Dallas 1.631
Singapore 767
Hefei 668
San Jose 411
Ashburn 243
Ho Chi Minh City 200
Hong Kong 131
Seoul 131
Hanoi 128
Beijing 100
São Paulo 79
Council Bluffs 73
Los Angeles 65
Moscow 62
New York 60
Chicago 46
Da Nang 33
The Dalles 33
Santa Clara 26
Haiphong 25
Rio de Janeiro 25
Falkenstein 23
Orem 23
Montreal 22
Seattle 22
Tokyo 22
Porto Alegre 21
Redondo Beach 21
Rome 21
Guayaquil 20
Nuremberg 20
Yubileyny 20
Atlanta 19
Denver 19
Frankfurt am Main 19
Medellín 19
Mexico City 19
Quito 19
Brooklyn 18
Warsaw 18
Curitiba 17
Johannesburg 16
Phoenix 16
Tashkent 16
Brasília 15
Lahore 15
Munich 15
Tianjin 15
Asunción 14
Chennai 14
Mumbai 14
Buenos Aires 13
Fortaleza 13
Stockholm 13
Belo Horizonte 12
Salt Lake City 12
Tampa 12
Baghdad 11
Biên Hòa 11
Lima 11
San Francisco 11
Santiago 11
Thái Bình 11
Bogotá 10
Bắc Giang 10
Bắc Ninh 10
Goiânia 10
Jeddah 10
Kuala Lumpur 10
New Delhi 10
Ninh Bình 10
Salvador 10
Toronto 10
Vienna 10
Baku 9
Boston 9
Caracas 9
Dhaka 9
Elk Grove Village 9
Hải Dương 9
Shanghai 9
Bangkok 8
Guarulhos 8
Hortolândia 8
Milan 8
Naples 8
Paris 8
Querétaro 8
São Gonçalo 8
Campinas 7
Ha Long 7
London 7
Vũng Tàu 7
Amman 6
Ancona 6
Belém 6
Bologna 6
Cairo 6
Can Tho 6
Totale 7.797
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Nome #
1,2,4-Oxadiazoles in medicinal chemistry: trends of the last years 2.902
Radiofarmaco per utilizzo diagnostico terapeutico in medicina nucleare e medicina radio guidata 121
H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer 117
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling 109
At long last potent and selective KDM5 inhibitors 105
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 99
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase 98
Preparation of substituted quinazoline derivatives as DNA methyltransferase inhibitors 96
Radiodrug for diagnostic/therapeutic use in nuclear medicine and radio-guided medicine 96
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection 92
Preparation of 7-nitro-2,1,3-benzoxadiazole derivatives for antitumor therapy 92
An improved multiplex RT–quantitative PCR assay can reveal sex-specific activity of transmission-blocking drugs on ex vivo gametocytes from Plasmodium falciparum asymptomatic infections 90
HAT inhibitors in cancer therapy 90
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 89
Activation and inhibition of sirtuins: From bench to bedside 89
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases 88
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation 88
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives 87
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies 87
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts 86
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents 85
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression 85
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile 84
An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors 84
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 82
SIRT5 regulation of ammonia-induced autophagy and mitophagy 81
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases 79
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications 77
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII 76
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells 76
Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer 75
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases 75
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells 75
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase 74
GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis 73
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability 72
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity 72
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains 72
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors 72
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma 71
Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors 70
Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni 69
Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells 69
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives 69
Targeting lysine deacetylases (KDACs) in parasites 68
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment 68
Enzyme kinetics and inhibition of histone acetyltransferase KAT8 68
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) 67
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions 66
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity 66
Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy 66
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities 63
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases 62
Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300 62
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones 61
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni 61
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells 59
Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies 59
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies 56
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells 56
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni 55
M6A reduction relieves FUS-associated ALS granules 55
p300/CBP-associated factor selectively regulates the extinction of conditioned fear 54
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile 54
Targeting histone demethylases: A new avenue for the fight against cancer 53
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells 53
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes 53
GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design 52
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer 52
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 52
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor 51
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells 51
Native mass spectrometry for proximity-inducing compounds: a new opportunity for studying chemical-induced protein modulation 51
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants 51
c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition 50
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression 50
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 49
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription 49
Sirtuin modulators: past, present, and future perspectives 49
Identification of novel quinazoline derivatives as potent antiplasmodial agents 49
The Two-Faced Role of SIRT6 in Cancer 48
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes 48
Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity 48
Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity 48
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells 47
Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia 46
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 46
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity 46
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer 46
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020) 45
Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies 45
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches 45
Sirtuin functions and modulation: from chemistry to the clinic 44
Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer’s Disease 44
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells 44
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53 44
From PARP1 to TNKS2 Inhibition: A Structure-Based Approach 44
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect 44
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1 44
Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues 44
Totale 9.489
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Categoria #
all - tutte 36.459
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.459
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/20253.014 0 0 0 0 22 455 1.138 428 262 102 146 461
2025/20269.932 430 1.154 2.221 1.443 609 282 539 161 2.392 701 0 0
Totale 12.946