Benvenuti nell'Anagrafe della Ricerca d'Ateneo

ROTILI, DANTE
 Distribuzione geografica
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Continente #
AS - Asia 4.453
NA - Nord America 4.148
EU - Europa 4.041
SA - Sud America 1.243
AF - Africa 117
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 14.009
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Nazione #
US - Stati Uniti d'America 3.986
NL - Olanda 1.917
SG - Singapore 1.715
RU - Federazione Russa 1.477
CN - Cina 1.196
BR - Brasile 911
VN - Vietnam 590
IT - Italia 339
BD - Bangladesh 222
HK - Hong Kong 153
KR - Corea 134
AR - Argentina 111
IN - India 99
DE - Germania 91
CA - Canada 72
EC - Ecuador 65
CO - Colombia 55
MX - Messico 48
ID - Indonesia 47
IQ - Iraq 40
GB - Regno Unito 39
ZA - Sudafrica 36
FR - Francia 32
JP - Giappone 29
TR - Turchia 29
PK - Pakistan 28
PH - Filippine 26
PY - Paraguay 26
AT - Austria 25
CL - Cile 23
VE - Venezuela 23
PL - Polonia 22
SA - Arabia Saudita 21
ES - Italia 19
UA - Ucraina 18
PE - Perù 16
UZ - Uzbekistan 16
MA - Marocco 15
SE - Svezia 13
EG - Egitto 12
MY - Malesia 12
AZ - Azerbaigian 11
JM - Giamaica 11
TH - Thailandia 11
TN - Tunisia 11
KZ - Kazakistan 10
FI - Finlandia 8
UY - Uruguay 8
DZ - Algeria 7
JO - Giordania 7
LT - Lituania 7
AL - Albania 5
BO - Bolivia 5
CR - Costa Rica 5
ET - Etiopia 5
HN - Honduras 5
IE - Irlanda 5
IL - Israele 5
KE - Kenya 5
NP - Nepal 5
OM - Oman 5
GT - Guatemala 4
LB - Libano 4
NG - Nigeria 4
PT - Portogallo 4
SY - Repubblica araba siriana 4
TW - Taiwan 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BH - Bahrain 3
CH - Svizzera 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
KH - Cambogia 3
LV - Lettonia 3
PA - Panama 3
QA - Qatar 3
XK - ???statistics.table.value.countryCode.XK??? 3
BF - Burkina Faso 2
BG - Bulgaria 2
BS - Bahamas 2
BY - Bielorussia 2
IR - Iran 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LK - Sri Lanka 2
MG - Madagascar 2
MW - Malawi 2
PS - Palestinian Territory 2
RO - Romania 2
RS - Serbia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BE - Belgio 1
BN - Brunei Darussalam 1
BT - Bhutan 1
BW - Botswana 1
Totale 13.982
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Città #
Amsterdam 1.866
Dallas 1.688
Singapore 779
Hefei 668
San Jose 593
Ashburn 377
Ho Chi Minh City 200
Hong Kong 142
Seoul 131
Hanoi 128
Beijing 114
New York 110
Los Angeles 100
São Paulo 79
Council Bluffs 73
Rome 70
Moscow 62
Chicago 53
Orem 39
Santa Clara 39
Denver 35
Milan 35
Da Nang 33
The Dalles 33
Brooklyn 29
Atlanta 28
Montreal 28
San Francisco 27
Seattle 27
Haiphong 25
Rio de Janeiro 25
Naples 24
Falkenstein 23
Tokyo 23
Mexico City 21
Porto Alegre 21
Redondo Beach 21
Guayaquil 20
Nuremberg 20
Toronto 20
Yubileyny 20
Frankfurt am Main 19
Medellín 19
Phoenix 19
Quito 19
Warsaw 18
Curitiba 17
Houston 16
Johannesburg 16
Tashkent 16
Brasília 15
Lahore 15
Munich 15
Tianjin 15
Asunción 14
Chennai 14
Mumbai 14
Boston 13
Buenos Aires 13
Buffalo 13
Fortaleza 13
London 13
Stockholm 13
Tampa 13
Belo Horizonte 12
Salt Lake City 12
Baghdad 11
Biên Hòa 11
Lima 11
Santiago 11
Thái Bình 11
Bogotá 10
Bologna 10
Bắc Giang 10
Bắc Ninh 10
Goiânia 10
Jeddah 10
Kuala Lumpur 10
New Delhi 10
Ninh Bình 10
Salvador 10
Vienna 10
Baku 9
Boardman 9
Caracas 9
Dhaka 9
Elk Grove Village 9
Hải Dương 9
Shanghai 9
Bangkok 8
Guarulhos 8
Hortolândia 8
Paris 8
Querétaro 8
São Gonçalo 8
Ancona 7
Campinas 7
Charlotte 7
Ha Long 7
Vũng Tàu 7
Totale 8.536
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Nome #
1,2,4-Oxadiazoles in medicinal chemistry: trends of the last years 2.933
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni 390
Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer 129
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling 127
Radiofarmaco per utilizzo diagnostico terapeutico in medicina nucleare e medicina radio guidata 127
H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer 120
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 116
At long last potent and selective KDM5 inhibitors 105
Preparation of substituted quinazoline derivatives as DNA methyltransferase inhibitors 102
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase 101
An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors 100
Radiodrug for diagnostic/therapeutic use in nuclear medicine and radio-guided medicine 98
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection 97
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies 96
An improved multiplex RT–quantitative PCR assay can reveal sex-specific activity of transmission-blocking drugs on ex vivo gametocytes from Plasmodium falciparum asymptomatic infections 94
Preparation of 7-nitro-2,1,3-benzoxadiazole derivatives for antitumor therapy 94
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 92
Activation and inhibition of sirtuins: From bench to bedside 92
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation 92
HAT inhibitors in cancer therapy 91
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts 90
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression 90
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives 89
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases 89
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile 87
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents 87
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 87
Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors 85
SIRT5 regulation of ammonia-induced autophagy and mitophagy 84
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII 82
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases 82
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 81
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases 80
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells 79
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions 78
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications 78
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability 77
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase 77
GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis 77
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains 77
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells 76
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells 75
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma 75
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors 74
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity 73
Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni 70
Targeting lysine deacetylases (KDACs) in parasites 70
Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells 70
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives 70
Enzyme kinetics and inhibition of histone acetyltransferase KAT8 70
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment 69
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) 68
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity 68
Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy 67
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities 65
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases 64
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress 64
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones 64
The Two-Faced Role of SIRT6 in Cancer 63
Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300 63
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer 61
Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications 61
From PARP1 to TNKS2 Inhibition: A Structure-Based Approach 61
Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies 61
Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes 60
M6A reduction relieves FUS-associated ALS granules 59
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells 58
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies 57
p300/CBP-associated factor selectively regulates the extinction of conditioned fear 57
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa 57
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni 57
Targeting histone demethylases: A new avenue for the fight against cancer 56
c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition 56
Prognostic Impact of H19/Cell Adhesion Molecules Circuitry on Prostate Cancer Biopsy 56
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants 56
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile 55
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells 55
Sirtuin modulators: past, present, and future perspectives 55
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes 55
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells 55
Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence 54
GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design 54
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription 54
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor 54
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 53
Native mass spectrometry for proximity-inducing compounds: a new opportunity for studying chemical-induced protein modulation 53
Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity 53
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer 52
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression 52
Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics 50
Identification of novel quinazoline derivatives as potent antiplasmodial agents 50
Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation 50
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells 49
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53 49
Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392 49
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes 49
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells 48
Sirtuin functions and modulation: from chemistry to the clinic 48
Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer’s Disease 48
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity 48
Totale 10.395
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Categoria #
all - tutte 41.191
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.191
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/20253.014 0 0 0 0 22 455 1.138 428 262 102 146 461
2025/202611.208 430 1.154 2.221 1.443 609 282 539 161 2.392 843 1.006 128
Totale 14.222