Benvenuti nell'Anagrafe della Ricerca d'Ateneo

ROTILI, DANTE
 Distribuzione geografica
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Continente #
AS - Asia 124
EU - Europa 112
NA - Nord America 59
SA - Sud America 3
OC - Oceania 1
Totale 299
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Nazione #
RU - Federazione Russa 87
SG - Singapore 76
US - Stati Uniti d'America 59
HK - Hong Kong 43
IT - Italia 10
NL - Olanda 7
FR - Francia 4
CN - Cina 3
PE - Perù 2
PT - Portogallo 2
BO - Bolivia 1
CZ - Repubblica Ceca 1
NZ - Nuova Zelanda 1
SE - Svezia 1
TH - Thailandia 1
TM - Turkmenistan 1
Totale 299
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Città #
Singapore 54
Hong Kong 43
Moscow 27
Seattle 18
Los Angeles 4
Amsterdam 2
Ardea 2
Beijing 2
Orlando 2
Rome 2
Turin 2
Ashgabat 1
Auckland 1
Fano 1
La Paz 1
Lima 1
Lisbon 1
Prague 1
Sant'Agata Bolognese 1
Sioux Falls 1
Stockholm 1
Totale 168
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Nome #
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII 5
Preparation of substituted quinazoline derivatives as DNA methyltransferase inhibitors 5
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases 5
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 5
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor 5
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8 5
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection 5
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery 5
Radiofarmaco per utilizzo diagnostico terapeutico in medicina nucleare e medicina radio guidata 5
Radiodrug for diagnostic/therapeutic use in nuclear medicine and radio-guided medicine 5
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni 5
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 4
Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence 4
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) 4
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection 4
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase 4
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability 4
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling 4
HAT inhibitors in cancer therapy 4
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 3
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions 3
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile 3
The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis 3
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells 3
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes 3
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties 3
Sirtuin functions and modulation: from chemistry to the clinic 3
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020) 3
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases 3
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile 3
Quinoline-based compounds can inhibit diverse enzymes that act on DNA 3
Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications 3
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa 3
Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer’s Disease 3
Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features 3
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells 3
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells 3
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer 3
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni 3
Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities 3
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53 3
Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis 3
Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells 3
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages 3
Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia 3
Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue 3
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans 3
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells 3
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey 3
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models 3
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives 3
One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones 3
SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells 3
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents 3
Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors 3
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 3
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors 3
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells 3
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress 3
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling 3
The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line 3
DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation 3
Uracil‐ and Pyridine‐Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells 3
Sirtuins as drug targets 3
Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies 3
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity 3
Targeting lysine deacetylases (KDACs) in parasites 3
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells 3
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1 3
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development 3
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer 3
Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity 3
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells 3
Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes 3
Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases 3
Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates 3
Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer 3
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains 3
M6A reduction relieves FUS-associated ALS granules 3
PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage 3
Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation 3
Emerging Therapeutic Potential of SIRT6 Modulators 3
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase 3
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment 3
The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides 3
Discovery of (Aryloxo propenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A 3
Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 3
Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies 3
SIRT5 regulation of ammonia-induced autophagy and mitophagy 3
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides 3
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases 3
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts 3
Preparation of 7-nitro-2,1,3-benzoxadiazole derivatives for antitumor therapy 3
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression 3
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes 3
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies 3
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants 3
At long last potent and selective KDM5 inhibitors 3
Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity 3
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 3
Totale 330
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Categoria #
all - tutte 2.304
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 2.304
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/2025485 0 0 0 0 22 455 8 0 0 0 0 0
Totale 485