Benvenuti nell'Anagrafe della Ricerca d'Ateneo

ROTILI, DANTE
 Distribuzione geografica
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Continente #
AS - Asia 3.392
NA - Nord America 2.634
EU - Europa 1.819
SA - Sud America 1.055
AF - Africa 77
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
Totale 8.982
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Nazione #
US - Stati Uniti d'America 2.552
SG - Singapore 1.559
RU - Federazione Russa 1.468
CN - Cina 1.038
BR - Brasile 823
VN - Vietnam 370
KR - Corea 130
AR - Argentina 89
IT - Italia 82
HK - Hong Kong 72
DE - Germania 67
EC - Ecuador 50
NL - Olanda 50
CA - Canada 36
BD - Bangladesh 33
ID - Indonesia 31
MX - Messico 31
IN - India 29
ZA - Sudafrica 27
AT - Austria 25
CO - Colombia 24
FR - Francia 22
GB - Regno Unito 22
PY - Paraguay 21
IQ - Iraq 19
JP - Giappone 17
PL - Polonia 16
ES - Italia 15
VE - Venezuela 14
CL - Cile 13
PE - Perù 13
SE - Svezia 12
PK - Pakistan 11
UA - Ucraina 11
EG - Egitto 10
TR - Turchia 10
MA - Marocco 9
UZ - Uzbekistan 8
KZ - Kazakistan 7
AZ - Azerbaigian 6
DZ - Algeria 6
FI - Finlandia 6
SA - Arabia Saudita 6
UY - Uruguay 6
JO - Giordania 5
LT - Lituania 5
OM - Oman 4
TN - Tunisia 4
AE - Emirati Arabi Uniti 3
DO - Repubblica Dominicana 3
HN - Honduras 3
LB - Libano 3
MY - Malesia 3
QA - Qatar 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
BH - Bahrain 2
BO - Bolivia 2
CH - Svizzera 2
IE - Irlanda 2
IL - Israele 2
IR - Iran 2
JM - Giamaica 2
KH - Cambogia 2
KW - Kuwait 2
LV - Lettonia 2
MW - Malawi 2
NG - Nigeria 2
NP - Nepal 2
PT - Portogallo 2
TH - Thailandia 2
AO - Angola 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CI - Costa d'Avorio 1
CM - Camerun 1
CR - Costa Rica 1
CZ - Repubblica Ceca 1
DM - Dominica 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GH - Ghana 1
GN - Guinea 1
GT - Guatemala 1
HT - Haiti 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MG - Madagascar 1
ML - Mali 1
MN - Mongolia 1
Totale 8.966
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Città #
Dallas 1.627
Hefei 668
Singapore 642
Ashburn 212
Ho Chi Minh City 132
Seoul 130
Beijing 83
Hanoi 74
Hong Kong 71
São Paulo 69
Moscow 61
Los Angeles 55
New York 46
Chicago 44
The Dalles 33
San Jose 25
Rio de Janeiro 24
Falkenstein 23
Seattle 22
Redondo Beach 21
Montreal 20
Nuremberg 20
Porto Alegre 20
Yubileyny 20
Denver 19
Brooklyn 18
Rome 18
Atlanta 17
Haiphong 17
Curitiba 16
Da Nang 16
Guayaquil 16
Tokyo 16
Munich 15
Brasília 14
Tianjin 14
Warsaw 14
Johannesburg 13
Phoenix 13
Quito 13
Santa Clara 13
Belo Horizonte 12
Salt Lake City 12
Stockholm 12
Tampa 12
Mexico City 11
Asunción 10
Fortaleza 10
Lima 10
San Francisco 10
Vienna 10
Buenos Aires 9
Bắc Giang 9
Chennai 9
Goiânia 9
Shanghai 9
Thái Bình 9
Biên Hòa 8
Bắc Ninh 8
Elk Grove Village 8
Hortolândia 8
Hải Dương 8
Mumbai 8
Orem 8
Paris 8
Querétaro 8
Salvador 8
Tashkent 8
Ha Long 7
Ninh Bình 7
São Gonçalo 7
Toronto 7
Ancona 6
Baku 6
Belém 6
Boston 6
Caxias do Sul 6
Council Bluffs 6
Guarulhos 6
Jundiaí 6
Lahore 6
Santo André 6
Uberlândia 6
Amman 5
Amsterdam 5
Bogotá 5
Bologna 5
Cairo 5
Campinas 5
Houston 5
London 5
Milan 5
Milwaukee 5
Niterói 5
Nova Iguaçu 5
Qingdao 5
Santiago 5
São José do Rio Preto 5
Wilmington 5
Ankara 4
Totale 4.833
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Nome #
1,2,4-Oxadiazoles in medicinal chemistry: trends of the last years 1.007
H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer 101
At long last potent and selective KDM5 inhibitors 94
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling 92
Radiofarmaco per utilizzo diagnostico terapeutico in medicina nucleare e medicina radio guidata 87
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 82
Radiodrug for diagnostic/therapeutic use in nuclear medicine and radio-guided medicine 82
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase 81
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation 80
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection 79
HAT inhibitors in cancer therapy 79
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 78
Preparation of substituted quinazoline derivatives as DNA methyltransferase inhibitors 77
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile 76
An improved multiplex RT–quantitative PCR assay can reveal sex-specific activity of transmission-blocking drugs on ex vivo gametocytes from Plasmodium falciparum asymptomatic infections 76
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 75
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases 75
Preparation of 7-nitro-2,1,3-benzoxadiazole derivatives for antitumor therapy 74
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression 74
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives 73
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents 72
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts 72
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications 70
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII 69
SIRT5 regulation of ammonia-induced autophagy and mitophagy 69
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases 68
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells 68
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells 67
Activation and inhibition of sirtuins: From bench to bedside 66
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity 66
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases 65
An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors 65
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma 64
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains 64
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives 63
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase 61
Targeting lysine deacetylases (KDACs) in parasites 60
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment 60
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies 60
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors 60
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity 60
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) 59
Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy 59
Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni 58
Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer 57
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability 57
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities 57
Enzyme kinetics and inhibition of histone acetyltransferase KAT8 57
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions 56
Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells 56
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni 56
Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors 55
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases 54
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies 53
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones 53
GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis 52
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells 52
Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300 50
Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies 49
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile 48
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells 47
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes 45
Native mass spectrometry for proximity-inducing compounds: a new opportunity for studying chemical-induced protein modulation 45
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants 44
p300/CBP-associated factor selectively regulates the extinction of conditioned fear 43
M6A reduction relieves FUS-associated ALS granules 43
Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity 42
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 41
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes 41
Targeting histone demethylases: A new avenue for the fight against cancer 40
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020) 40
c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition 40
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni 40
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 40
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer 40
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression 40
Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity 40
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor 39
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells 38
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity 38
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription 38
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells 38
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1 38
Identification of novel quinazoline derivatives as potent antiplasmodial agents 38
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 37
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer 37
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development 37
Sirtuin modulators control reactive gliosis in an in vitro model of alzheimer's disease 37
Sirtuin functions and modulation: from chemistry to the clinic 36
GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design 36
One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones 36
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells 36
Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies 36
Quinoline-based compounds can inhibit diverse enzymes that act on DNA 35
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence 35
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors 35
The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line 35
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity 35
Modulation of Virulence-Associated Traits in Aspergillus fumigatus by BET Inhibitor JQ1 35
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer 34
Totale 6.499
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Categoria #
all - tutte 31.131
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.131
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/20253.014 0 0 0 0 22 455 1.138 428 262 102 146 461
2025/20266.166 430 1.154 2.221 1.443 609 282 27 0 0 0 0 0
Totale 9.180